|
|||||
|
|
Response of bilateral breasts to the endogenous hormonal fluctuation in a menstrual cycle evaluated using 3D MRI |
|
| Authors: | Jeon-Hor Chen Siwa Chan Dah-Cherng Yeh Peter T. Fwu Muqing Lin Min-Ying Su |
| Affiliation: | 1. Tu & Yuen Center for Functional Onco-Imaging, Department of Radiological Sciences, University of California, Irvine, California, United States;2. Department of Radiology, E-Da Hospital and I-Shou University, Kaohsiung 82445, Taiwan;3. Department of Radiology, Chi-Mei Medical Center, Tainan 70457, Taiwan;4. Department of Radiology, Taichung Veterans General Hospital, Taichung, Taiwan;5. Department of Surgery, Taichung Veterans General Hospital, Taichung, Taiwan |
| Abstract: | The normal breast tissue responds to the fluctuation of endogenous hormones during a menstrual cycle (MC) and shows changes in breast density. The changes between left and right breasts of the same women were compared to evaluate the symmetrical response. Twenty-four healthy women were recruited in this study. Four weekly magnetic resonance imaging (MRI) studies were performed during one MC. A computer algorithm was used to segment the breast and the fibroglandular tissue to measure the fibroglandular tissue volume (FV) and three morphological parameters: circularity, convexity and irregularity. The coefficient of variation (CV) for each parameter measured among four MRI studies was calculated; also, the maximal percent change between two MRI studies that show the highest and the lowest FV was calculated. These parameters measured from left and right breasts were compared using Pearson correlation. |
| Keywords: | Breast Endogenous hormone Menstrual cycle MRI Fibroglandular tissue volume |
| 本文献已被 ScienceDirect 等数据库收录！ | |