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Three novel diepoxy tetrahydrochromones from agarwood artificially produced by intentional wounding
Authors:Toru Yagura  Michiho Ito  Gisho Honda
Institution:a Department of Pharmacognosy, Graduate School of Pharmaceutical Sciences, Kyoto University, 46-29 Yoshida-Shimoadachi-cho, Sakyo-ku, Kyoto 606-8501, Japan
b Tsukuba Medicinal Plant Research Station, National Institute of Health Sciences, Ministry of Health, Labour and Welfare, 1 Hachimandai, Tsukuba 305-0843, Japan
Abstract:Three novel diepoxy tetrahydrochromones, oxidoagarochromones A (1), B (2), and C (3), were isolated from agarwood artificially produced by intentional wounding of Aquilaria crassna. Inductive production of these compounds was also confirmed at the early stage of wounding in A. sinensis and A. crassna. These diepoxy tetrahydrochromones would play an important role in understanding the biosynthesis of chromone derivatives in agarwood.
Keywords:Diepoxy tetrahydrochromone  Oxidoagarochromone  Agarwood  Aquilaria crassna  Aquilaria sinensis  Thymelaeaceae  Intentional wounding
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