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NaIO4-mediated C-H activation of alkylbenzenes and alkanes with LiBr
Authors:Tanveer M Shaikh
Institution:Chemical Engineering and Process Development Division, National Chemical Laboratory, Pashan Road, Pune 411 008, India
Abstract:NaIO4 oxidizes lithium bromide efficiently under acidic conditions to functionalize alkylbenzenes and alkanes and produce the corresponding bromo and acetoxy derivatives in excellent yields. The protocol also demonstrates the direct conversion of cyclohexane into trans-1,2-dibromocyclohexane in moderate yield.
Keywords:C-H activation  Alkylbenzenes  Alkanes  NaIO4  Lithium bromide
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