NaIO4-mediated C-H activation of alkylbenzenes and alkanes with LiBr |
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Authors: | Tanveer M Shaikh |
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Institution: | Chemical Engineering and Process Development Division, National Chemical Laboratory, Pashan Road, Pune 411 008, India |
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Abstract: | NaIO4 oxidizes lithium bromide efficiently under acidic conditions to functionalize alkylbenzenes and alkanes and produce the corresponding bromo and acetoxy derivatives in excellent yields. The protocol also demonstrates the direct conversion of cyclohexane into trans-1,2-dibromocyclohexane in moderate yield. |
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Keywords: | C-H activation Alkylbenzenes Alkanes NaIO4 Lithium bromide |
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