A novel 3,8-seco-taxane metabolite from the seeds of the Chinese yew, Taxus mairei |
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| Authors: | Qing-Wen Shi Zuo-Ping Li Hiromasa Kiyota |
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| Affiliation: | a Department of Natural Product Chemistry, School of Pharmaceutical Sciences, Hebei Medicinal University, 336 Zhongshan East Road, 050017 Shijiazhuang, Hebei Province, PR China
b Department of Bioscience and Biotechnology for Future Bioindustry, Graduate School of Agricultural Science, Tohoku University, 1-1 Tsutsumidori-Amamiya, Aoba-ku, Sendai 981-8555, Japan |
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| Abstract: | The structure of a novel 3,8-seco-bicyclic taxanoid metabolite, isolated from the methanol extract of seeds of the Chinese yew, Taxus mairei, was established as (11αH)-3,8-seco-taxa-3E,7E,12(18)-triene-2α,6α,9β-triol (1) on the basis of spectral analysis including 1H NMR, 13C NMR, HMQC, HMBC, NOESY and HR-FABMS. |
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| Keywords: | Taxanes Bicyclic taxanes Taxus mairei Isolation |
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