Stereoselective synthesis of spiroannulated cyclopentenones by the Pauson-Khand reaction on carbohydrate derived enynes |
| |
| Authors: | Srinivas Hotha Sushil K Maurya Mukund K Gurjar |
| |
| Institution: | Combi Chem—Bio Resource Center, Division of Organic Chemistry: Synthesis, National Chemical Laboratory, Pune 411 008, India |
| |
| Abstract: | The stereoselective synthesis of spiroannulated cyclopentenones by the Pauson-Khand reactions on hexose and pentose derived enynes was achieved under carbon monoxide free conditions using a stoichiometric quantity of Co2(CO)8. The cobalt complex of the alkyne was cleaved using dimethoxyethane-acetonitrile at 85 °C to furnish spiroannulated cyclopentenones in 75-94% yields. |
| |
| Keywords: | Pauson-Khand reaction Cyclopentenone Diversity oriented synthesis Carbohydrates |
| 本文献已被 ScienceDirect 等数据库收录！ |
