Studies towards the total synthesis of Sch 56036; isoquinolinone synthesis and the synthesis of phenanthrenes
Authors:
Edward R. Walker
Affiliation:
Department of Chemistry, Imperial College London, London SW7 2AZ, England, UK
Abstract:
The isoquinolinone hemisphere of Sch 56036 has been prepared using a modified Pomeranz-Fritsch reaction and the synthesis of the phenanthrene core has been modelled via a Suzuki coupling and subsequent ring closing metathesis.