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One-pot synthesis of dihydropyrimidiones catalyzed by strontium(II) triflate under solvent-free conditions |
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| Authors: | Weike Su Jianjun Li Yinchu Shen |
| Affiliation: | a Zhejiang Key Laboratory of Pharmaceutical Engineering, College of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou 310014, PR China b Zhejiang Hisoar Pharmaceutical Co., Ltd, Taizhou 318000, PR China c Shanghai Pesticide Research Institute, Shanghai 200032, PR China |
| Abstract: | A simple, efficient and practical procedure for the Biginelli reaction using strontium(II) triflate [Sr(OTf)2] as a novel catalyst is described under solvent-free conditions in high yields. The catalyst exhibited remarkable reactivity and it is reusable. Some of dihydropyrimidiones showed strong pesticidal activity. |
| Keywords: | Biginelli reaction Solvent-free Strontium(II) triflate Dihydropyrimidiones Bioactivity |
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