Syntheses of glycodendrimers having scyllo-inositol as the scaffold |
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Authors: | Nan-Young Lee |
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Affiliation: | Department of Chemistry, Division of Molecular and Life Sciences, Pohang University of Science and Technology, Pohang 790-784, Korea |
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Abstract: | Synthetic glycoconjugated dendrimers have emerged as important functional glycomimetics for studying multivalency effects in the cell-cell communications. We report herein, a synthetic route to functionalized glycodendrimers with scyllo-inositol as the scaffold, which have a directed geometry; one side of the dendrimers is designed for ready attachment to the AFM probe/solid matrix, and the other to have a varying number of a sugar. |
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Keywords: | Glycomics Glycoside cluster effect Glycodendrimer scyllo-Inositol PAMAM |
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