Reactions between isocyanides and dialkyl acetylenedicarboxylates in the presence of 1,2-diacylhydrazines. One-pot synthesis of highly functionalized pyrazoles |
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| Authors: | Mehdi Adib Mohammad Hosein Sayahi Sahar Rahbari |
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| Affiliation: | Department of Chemistry, Faculty of Science, University of Tehran, PO Box 14155-6455, Tehran, Iran |
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| Abstract: | The reactive 1:1 intermediate produced in the reaction between isocyanides and dialkyl acetylenedicarboxylates was trapped with 1,2-diacylhydrazines to yield highly functionalized pyrazoles in good yields. |
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| Keywords: | Isocyanides Acetylenic esters Pyrazoles Three-component reactions |
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