Six new indole alkaloids from Gelsemium sempervirens Ait. f. |
| |
| Authors: | Noriyuki Kogure |
| |
| Institution: | Graduate School of Pharmaceutical Sciences, Chiba University, 1-33 Yayoi-cho, Inage-ku, Chiba 263-8522, Japan |
| |
| Abstract: | One new yohimbane and five new sarpagine-type indole alkaloids were isolated from the radix of Gelsemium sempervirens Ait. f., and their structures were determined by spectroscopic analysis, chemical conversion or total synthesis. It was found that 2-acyl sarpagine-type alkaloids possessing an Nb-methyl group take a keto-amino structure or a transannular form in solution depending on the solvent. |
| |
| Keywords: | Indole alkaloid Gelsemium Structure elucidation NMR Total synthesis Isomerization Solvent effect |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
