Regioselective synthesis of functionally congested biaryls through a novel C-C bond formation reaction |
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| Authors: | Atul Goel Fateh Veer Singh |
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| Institution: | Division of Medicinal and Process Chemistry, Central Drug Research Institute, Lucknow 226 001, India |
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| Abstract: | An expeditious synthesis of unsymmetrical biaryls functionalized with electron-withdrawing or -donating substituents is described and illustrated by the carbanion-induced ring transformation of 2H-pyran-2-ones with malononitrile in excellent yields. |
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| Keywords: | Biaryl Phenyl acetone Lactone Malononitrile Pyran-2-one |
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