Molecular iodine: a powerful catalyst for the easy and efficient synthesis of quinoxalines |
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Authors: | Shivaji V More |
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Institution: | Department of Chemistry, National Taiwan Normal University 88, Sec. 4, Tingchow Road, Taipei, Taiwan 116, ROC |
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Abstract: | Various biologically important quinoxaline derivatives were efficiently synthesized in excellent yields using inexpensive, nontoxic, and readily available bench top chemical, iodine in catalytic amount (10 mol %). Besides this, a systematic study was carried out to evaluate parameters such as solvent and catalyst loading. Several aromatic as well as aliphatic 1,2-diketones and aromatic 1,2-diamines, such as substituted phenylene diamines, tetra amines were further subjected to condensation using catalytic amounts of iodine to afford the products in excellent yield. |
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Keywords: | 1 2-Diketones Quinoxalines Iodine Catalytic amount Ecofriendly process |
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