A new convenient synthesis of functionalized 2,3-dihydro-4-pyridones |
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| Authors: | Jan Svetlik Viktor Kettmann |
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| Institution: | a Department of Pharmaceutical Analysis and Nuclear Pharmacy, Faculty of Pharmacy, Comenius University, Odbojarov 10, SK-832 32 Bratislava, Slovak Republic
b Department of Organic Chemistry, Jagiellonian University, Ingardena 3, PL 30-060 Krakow, Poland |
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| Abstract: | A simple, efficient and diastereoselective route to 2,3,6-trisubstituted 2,3-dihydro-4-pyridones from methyl 3,5-dioxohexanoate, aryl aldehydes and ammonium acetate is described. |
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| Keywords: | 2 3-Dihydro-4-pyridone 3 5-Dioxohexanoate Aldehyde Diastereoselectivity |
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