One-pot synthesis of N-allylthioureas using supported reagents |
| |
| Authors: | Tadashi Aoyama Sumiko Murata Toshio Takido |
| |
| Institution: | a Department of Materials and Applied Chemistry, College of Science and Technology, Nihon University, Kanda Surugadai, Chiyoda-ku, Tokyo 101-8308, Japan
b Department of Applied Chemistry, Shibaura Institute of Technology, Shibaura, Minato-ku, Tokyo 108-8548, Japan |
| |
| Abstract: | A simple and efficient method has been developed for the synthesis of N-allylthioureas from allylic bromides in one-pot by using a supported reagents system, KSCN/SiO2-RNH3OAc/Al2O3, in which allyl bromide reacts first with KSCN/SiO2 and the product, allyl isothiocyanate, reacts with RNH3OAc/Al2O3 to give the final product, N-allylthiourea, in good yield. |
| |
| Keywords: | Thiourea Supported reagents One-pot synthesis |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
