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Highly sensitive and specific real-time PCR by employing serial invasive reaction as a sequence identifier for quantifying EGFR mutation abundance in cfDNA |
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| Authors: | Xiang Zheng Wan Ruixuan Zou Bingjie Qi Xiemin Huang Qing Kumar Shalen Pitman Janet L. Zhou Guohua Song Qinxin |
| Affiliation: | 1.Key Laboratory of Drug Quality Control and Pharmacovigilance of Ministry of Education, School of Pharmacy, China Pharmaceutical University, Nanjing, 210009, Jiangsu, China ;2.Department of Pharmacology, Jinling Hospital, Medical School of Nanjing University, Nanjing, 210002, Jiangsu, China ;3.School of Biological Sciences, Victoria University of Wellington, Wellington, 6140, New Zealand ; |
| Abstract: | Analytical and Bioanalytical Chemistry - Detection of EGFR mutations in circulating cell-free DNA (cfDNA) is beneficial to monitor the therapeutic effect, tumor progression, and drug resistance in... |
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