Fluorescence studies of protein thermostability in ionic liquids |
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| Authors: | Baker Sheila N McCleskey T Mark Pandey Siddharth Baker Gary A |
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| Institution: | Chemistry Division, MS J514, Los Alamos National Laboratory, Los Alamos, NM 87545, USA. |
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| Abstract: | Using the single tryptophan residue in the sweet protein monellin as a spectroscopic handle, we show the extreme thermodynamic stabilization offered by an ionic liquid; T(un) approximately 105 degrees C in C4mpy]Tf2N] compared to 40 degrees C in bulk water. |
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