Differential Pulse Voltammetric Determination of Local Anesthetics Heptacaine,Carbisocaine and Pentacaine at DNA Modified Screen‐Printed Electrode

A procedure for the differential pulse voltammetric determination of three local anesthetics (Heptacaine, Carbisocaine and Pentacaine) at a screen‐printed electrode surface modified with the dsDNA layer is described. The detection limits obtained after 120 s drug accumulation from 0.01 M phosphate buffer solution pH 6.96 are 0.02 μM (Pentacaine) and 0.03 μM (Carbisocaine and Heptacaine). The method was applied to the determination of Carbisocaine in spiked serum.