Convenient stereoselective synthesis of some 3-aminosteroid scaffolds |
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| Authors: | Eirik Johansson Solum Yasser Mahmoud A. Mohamed |
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| Affiliation: | 1. Faculty of Health Sciences, NORD University, Namsos, Norway;2. eirik.j.solum@nord.no;4. Photochemistry Department, National Research Center, Giza, Egypt |
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| Abstract: | AbstractAn efficient stereoselective synthesis 3α- and 3β-aminoandrostan-17-one and 3α-amino dehydroepiandrosten-17-one based on a Mitsunobu reaction has been developed, using azide as the ammonia equivalent. All the products were isolated in high yield. |
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| Keywords: | Aminosteroids Staudinger reaction Mitsunobu reaction |
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