The first synthesis of a thioglycoside analogue of the immunostimulant KRN7000 |
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| Authors: | Dere Ravindra T Zhu Xiangming |
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| Institution: | Centre for Synthesis and Chemical Biology, UCD School of Chemistry and Chemical Biology, University College Dublin, Belfield, Dublin 4, Ireland. |
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| Abstract: | The first total synthesis of a thioglycoside analogue of KRN7000, a potential immunostimulant, is described. Two key intermediates are alpha-galactosyl thiol 4 and phytosphingosine derivative 5, which were both prepared from D-galactose. |
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