首页 | 本学科首页   官方微博 | 高级检索  
     


Recovery of 177Lu from Irradiated HfO2 Targets for Nuclear Medicine Purposes
Authors:Andrey G. Kazakov  Taisya Y. Ekatova  Julia S. Babenya  Sergey S. Belyshev  Vadim V. Khankin  Alexander A. Kuznetsov  Sergey E. Vinokurov  Boris F. Myasoedov
Affiliation:1.Radiochemistry Laboratory, Vernadsky Institute of Geochemistry and Analytical Chemistry of the Russian Academy of Sciences (GEOKHI RAS), Kosygin St., 19, 119991 Moscow, Russia; (T.Y.E.); (J.S.B.); (S.E.V.); (B.F.M.);2.Skobeltsyn Institute of Nuclear Physics, Lomonosov Moscow State University, Leninskie Gory, 1, Bld. 2, 119991 Moscow, Russia; (S.S.B.); (V.V.K.); (A.A.K.);3.Department of Physics, Lomonosov Moscow State University, Leninskie Gory, 1, Bld. 2, 119991 Moscow, Russia
Abstract:A new method of production of one of the most widely used isotopes in nuclear medicine, 177Lu, with high chemical purity was developed; this method includes irradiation of the HfO2 target with bremsstrahlung photons. The irradiated target was dissolved in HF and then diluted and placed onto a column filled with LN resin. Quantitative sorption of 177Lu could be observed during this process. The column later was rinsed with the mixture of 0.1 M HF and 1 M HNO3 and then 2 M HNO3 to remove impurities. Quantitative desorption of 177Lu was achieved by using 6 M HNO3. The developed method of 177Lu production ensures high purification of this isotope from macroquantities of hafnium and zirconium and radioactive impurities of carrier-free yttrium. The content of 177mLu in 177Lu in photonuclear production was determined. Due to high chemical and radionuclide purity, 177Lu obtained by the developed method can be used in nuclear medicine.
Keywords:177Lu   extraction chromatography   photonuclear reactions   radiochemical recovery   nuclear medicine
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号