Heteroatomic derivatives of aziridine. 14. Reactions of 1-(carbomethoxyethyl)-, 1-[1,2-bis(carbethoxy)ethyl]-, and 1-[1,2-bis(carbomethoxy)vinyl]aziridine with thiols, 1,2-ethanedithiol,and thiolcarboxylic acids

The reactions of 1-(carbomethoxyethyl)-, 1-1,2-bis(carbethoxy)-ethyl]-, and 1-1,2-bis(carbomethoxy)vinyl]aziridine with thiols and thiolcarboxylic acids produce the corresponding sulfides and esters of S-substituted N-(2-mercaptoethyl) amino acids. The reaction of 1-1,2-bis(carbethoxy)ethyl]aziridine with 1,2-ethane-dithiol results in the formation of {1,8-bis1,2-bis(carbethoxy)-ethyl]amino}-3,6-dithiaoctane. Cyclization of the latter by condensation with phthaloyl chloride gives 9,10-benzo-8,11-dioxo-1,4-dithia-7,12-bis1,2-bis(carbethoxy)ethyl]-7,12-diazacyclotetradec-9-ene.For report 13 see 1].Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 10, pp. 1340–1342, October, 1984.