首页 | 本学科首页   官方微博 | 高级检索  
     检索      

Surface engineering of carbon dots for highly sensitive α-glucosidase assay and inhibition evaluation
作者姓名:Meijuan Liang  Gege Song  Yeqing Wan  Yingying Chen  Fuan Wang  Xiaoqing Liu
作者单位:2. Oil Crops Research Institute, Chinese Academy of Agricultural Sciences
基金项目:supported by National Natural Science Foundation of China (Nos. 32202171, 22274121 and 22274123);
摘    要:Monitoring α-glucosidase(α-Glu) activity is of great significance for the early diagnosis of type Ⅱ diabetes. Here the blue fluorescent carbon dots(CDs) were integrated with two different recognizing molecules, β-cyclodextrin and phenylboronic acid, for assembling a multifunctional CDs(mCDs) nanoplatform for sensitively analyzing α-Glu and its inhibitors. The hydrolyzed product of 4-nitrophenyl-α-D-glucopyranoside(α-Glu substrate), p-nitrophenol, could efficiently quench the fluorescence of mCDs...

设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号