Synthesis of 6-Heterocyclically Appended Tri-<Emphasis Type="Italic">O</Emphasis>-methyl Protected 6-Desmethyl Emodin Derivatives |
| |
| Authors: | Tarek A?Salama Bernd?Lackner Email author" target="_blank">Heinz?FalkEmail author |
| |
| Institution: | (1) Institute of Organic Chemistry, Johannes Kepler University, A-4040 Linz, Austria |
| |
| Abstract: | Summary. A convenient synthesis of several 6-heterocyclically appended tri-O-methyl 6-desmethyl emodin derivatives including the tetrazolyl, oxazolyl, oxazolinyl, benzimidazolyl, benzoxazolyl, and benzothiazolyl derivatives of potential biological and medicinal interest was achieved starting from the tri-O-methyl protected emodin aldehyde or nitrile. In addition, these derivatives could serve as synthons for heterocyclic hypericin derivatives. |
| |
| Keywords: | , 9,10-Anthraquinones, Heterocycles, NMR Structure elucidation, Tri-O-methylemodin aldehyde, Tri-O-methylemodin nitrile, |
| 本文献已被 SpringerLink 等数据库收录！ |
|
