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Recent development on peptide-based probes for multifunctional biomedical imaging |
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| Authors: | Yuling Xu Mei Tian Hong Zhang Yuling Xiao Xuechuan Hong Yao Sun |
| Institution: | 1. Key Laboratory of Pesticides and Chemical Biology, Ministry of Education, Hubei International Scientific and Technological Cooperation Base of Pesticide and Green Synthesis, Chemical Biology Center, College of Chemistry, Central China Normal University, Wuhan 430079, China;2. State Key Laboratory of Virology, Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (MOE), Wuhan University School of Pharmaceutical Sciences, Wuhan 430071, China;3. Department of Nuclear Medicine, The Second Hospital of Zhejiang University School of Medicine, Hangzhou 310009, China |
| Abstract: | Peptide-based probes play prominent roles in biomedical research due to their promising properties such as high biocompatibility, fast excretion, favorable pharmacokinetics as well as easy and robust preparation. Considering the translation of imaging probes into clinical applications, peptide-based probes remain to be the most desirable and optimal candidates. This review summarized the development of peptide-based probes with promising imaging modalities and highlighted the successful applications for in vivo biomedical imaging. |
| Keywords: | Peptide-based probes Biomedical imaging Positron emission tomography Near-infrared dualmodal imaging |
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