Light-triggered release of insecticidally active spirotetramat-enol |
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Authors: | Zhiping Xu Zhenhong Gao Xusheng Shao |
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Institution: | a Shanghai Key Laboratory of Chemical Biology, School of Pharmacy, East China University of Science and Technology, Shanghai 200237, China;
b State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai 200237, China |
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Abstract: | Spirotetramat metabolizes to its active enol form in the plant. We described here a photocaged pesticide delivery system that can release insecticidal spirotetramat enol form upon light irradiation. Covalently linking spirotetramat-enol with photoresponsive coumarin generated the caged insecticide. The photophysical and photochemical properties, deprotection photolysis and insecticidal activities of the caged spirotetramat enol were studied. This light-triggered system can undergo cleavage to release free spirotetramat enol form at the presence of blue light (420 nm) or sunlight. Bioassays indicated that the triggered molecule has no obvious insecticidal activity against Aphis craccivora Koch at dark and could be activated by light to release the insecticidal ingredients, which provides precise control over insecticide delivery. |
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Keywords: | Photocage Spirotetramat enol Coumarin Insecticide Light |
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