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Designed evolution of artificial metalloenzymes: protein catalysts made to order
Authors:Creus Marc  Ward Thomas R
Affiliation:Department of Cellular and Molecular Biology, University of Neuchatel, Rue Emile-Argand 11, C.P. 158, Neuchatel, CH-2009, Switzerland. marc.creus@unine.ch
Abstract:Artificial metalloenzymes based on biotin-streptavidin technology, a "fusion" of chemistry and biology, illustrate how asymmetric catalysts can be improved and evolved using chemogenetic approaches.
Keywords:
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