Biosynthèse de la farnésylacétone-(E,E) par les glandes androgènes du crabe carcinus maenas

Biosynthesis of E, E-farnesylacetone by the andogenic glands of the crab Carcinus maenas Using sodium acetate-1,2-¹⁴C] or mevalonic acid-2-¹⁴C], the biosynthesis of (E,E)-farnesylacetone 1 by the androgenic glands of the crab Carcinus maenas, kept as organ subculture is demonstrated. Ozonolysis of the NaBH₄ reduction product 3 leads to three fragments the radioactivity of which has been measured after isolation by GC. It is thus established that the biosynthesis of 1 proceeds through geranylgeraniol. The hexahydroderivative 2 is not labelled in the two experiments.