儿茶素-银纳米复合材料的制备及其应用

探索了以植物活性成分儿茶素作为还原剂和保护剂一步水热法合成儿茶素-银纳米复合材料,并进一步测试了纳米复合材料的抑菌活性。 紫外可见吸收光谱(UV-Vis)和红外光谱(FTIR)测定证明制备得到了儿茶素包裹的银纳米粒子。 透射电子显微镜(TEM)和X射线衍射(XRD)结果显示银纳米粒子的平均粒径为22.7 nm,并具有面心立方晶体结构。 抑菌活性实验结果表明,儿茶素-银纳米复合粒子对大肠杆菌、金黄色葡萄球菌以及白色念球菌都有很强抑制作用,尤其对白色念球菌的抑制作用最强,其最低抑制浓度(MIC)和最低杀菌浓度(MBC)分别为19.63和39.26 μg/mL。 儿茶素-银纳米粒子强抑菌活性可归因于其表面银离子的持续释放,有望应用于长效抑菌制剂产品。

Preparation and Application of Catechin-Silver Nanocomposites

In this study, we explored a one-step hydrothermal synthesis method to synthesize catechin-silver nanocomposite wherein catechin was acted as the reduction agent and protection agent. The ultrviolet-visible (UV-Vis) and Fourier transform infrared spectroscopy(FTIR) measurements confirm that the obtained nanomaterials are catechin-capped Ag nanoparticles. Transmission electron microscopy(TEM) and X-ray diffraction(XRD) results indicate that the average diameter of the Ag nanoparticles is 22.7 nm, and the Ag nanoparticles have the face centered cubic crystal structure. We further studied the antibacterial activity of catechin-silver nanoparticles. The results of bacteriostatic experiments reveal that the catechin-silver nanoparticles have a strong inhibitory effect on E.coli, S.aureus and C.albicans. The minimal inhibitory concentration (MIC) and minimal bactericidal concentration (MBC) for C.albicans is 19.63 and 39.26 μg/mL, respectively. The inhibitory activity of catechin-silver nanoparticles can be attributed to the continuous release of Ag⁺ from their surface. The catechin-silver nanocomposite is expected to be used in long-acting antibacterial agents.