| Recognition of Protein Native Folds Using a Continuous Potential Function |
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| 引用本文： | WANG Yu-hong,LU Zhi-bin and LI Wei(Department of Molecular Biology,Jilin University,Changchun,130023 ). Recognition of Protein Native Folds Using a Continuous Potential Function[J]. 高等学校化学研究, 1994, 0(2) |
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| 作者姓名： | WANG Yu-hong LU Zhi-bin and LI Wei(Department of Molecular Biology Jilin University Changchun 130023 ) |
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| 作者单位： | Department of Molecular Biology，Jilin University，Changchun，130023 |
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| 摘 要： | ＲｅｃｏｇｎｉｔｉｏｎｏｆＰｒｏｔｅｉｎＮａｔｉｖｅＦｏｌｄｓＵｓｉｎｇａＣｏｎｔｉｎｕｏｕｓＰｏｔｅｎｔｉａｌＦｕｎｃｔｉｏｎＷＡＮＧＹｕ－ｈｏｎｇ，ＬＵＺｈｉ－ｂｉｎａｎｄＬＩＷｅｉ（ＤｅｐａｒｔｍｅｎｔｏｆＭｏｌｅｃｕｌａｒＢｉｏｌｏｇｙ，Ｊｉ...
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Recognition of Protein Native Folds Using a Continuous Potential Function |
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| WANG Yu-hong,LU Zhi-bin and LI Wei. Recognition of Protein Native Folds Using a Continuous Potential Function[J]. Chemical Research in Chinese University, 1994, 0(2) |
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| Authors: | WANG Yu-hong LU Zhi-bin LI Wei |
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| Abstract: | e report a simple continuous potential function that can recognize proteinchains' native folds from tens of thousands of alternative ones. Empirical parame-ters for this potential function were obtained by a neural network learning oversamples generated from PDB structural data.Hydrophobic interactions were foundto be mainly responsible for stabilization of the protein' s native fold. The inter-chain interaction was found indispensable in stabilizing some protein chains' nativeconformation. |
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| Keywords: | Recognition Protein native fold Function |
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