| Recognition of Protein Native Folds Using a Continuous Potential Function |
| |
| 作者姓名： | WANG Yu-hong LU Zhi-bin and LI Wei |
| |
| 作者单位： | Department of Molecular Biology，Jilin University，Changchun，130023 |
| |
| 摘 要： | ＲｅｃｏｇｎｉｔｉｏｎｏｆＰｒｏｔｅｉｎＮａｔｉｖｅＦｏｌｄｓＵｓｉｎｇａＣｏｎｔｉｎｕｏｕｓＰｏｔｅｎｔｉａｌＦｕｎｃｔｉｏｎＷＡＮＧＹｕ－ｈｏｎｇ，ＬＵＺｈｉ－ｂｉｎａｎｄＬＩＷｅｉ（ＤｅｐａｒｔｍｅｎｔｏｆＭｏｌｅｃｕｌａｒＢｉｏｌｏｇｙ，Ｊｉ...
|
Recognition of Protein Native Folds Using a Continuous Potential Function |
| |
| WANG Yu-hong,LU Zhi-bin and LI Wei.Recognition of Protein Native Folds Using a Continuous Potential Function[J].Chemical Research in Chinese University,1994(2). |
| |
| Authors: | WANG Yu-hong LU Zhi-bin and LI Wei |
| |
| Abstract: | e report a simple continuous potential function that can recognize proteinchains' native folds from tens of thousands of alternative ones. Empirical parame-ters for this potential function were obtained by a neural network learning oversamples generated from PDB structural data.Hydrophobic interactions were foundto be mainly responsible for stabilization of the protein' s native fold. The inter-chain interaction was found indispensable in stabilizing some protein chains' nativeconformation. |
| |
| Keywords: | Recognition Protein native fold Function |
| 本文献已被 CNKI 等数据库收录！ |
