Quantification and confirmation of priority organic micropollutants in water by LC-tandem mass spectrometry |
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Authors: | Elena Pitarch José M Marin Francisco Lopez Elbert Hogendoorn |
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Institution: | 1. Research Institute for Pesticides and Water, University Jaume I , Castellón, Spain;2. Laboratory for Analytical Chemistry , National Institute for Public Health and the Environment (RIVM) , Bilthoven, The Netherlands |
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Abstract: | Liquid chromatography coupled to tandem mass spectrometry with a triple quadrupole analyser was used to determine selected (medium) polar organic pollutants—isoproturon, diuron and pentachlorophenol, as the herbicides simazine, atrazine, terbuthilazine, alachlor, and metolachlor—in treated water from urban solid-waste leachates. Two millilitres of water was preconcentrated by on-line trace enrichment (solid-phase extraction liquid chromatography) which allowed rapid analysis, but still with a satisfactory sensitivity, as the limits of quantification were 0.05?µg?L?1, while the limits of detection were in the range of 0.001–0.01?µg?L?1. Confirmation of the identity of compounds was ensured by the use of two tandem mass spectrometry transitions. Moreover, a study of matrix effects was thoroughly investigated by applying the developed procedure to different ground and surface waters. A simple dilution of the water sample with high-performance-liquid-chromatography-grade water was sufficient to minimize and/or remove this undesirable effect in all water samples tested, this approach being feasible due to the excellent sensitivity of the method. |
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Keywords: | Organic pollutants Water analysis Municipal solid waste leachates LC-MS Matrix effects Tandem mass spectrometry |
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