Development of a method for the complex isolation of physiologically active components from bee venom

A method is proposed for isolating the main components (melittin, apamin, and phospholipase A₂ from the venom of the bee Apis mellifera using HPLC, and the synthesis of two sorbents for fractionating these peptides is described.A. S. Sadykov Institute of Biooganic Chemistry, Academy of Sciences of the Republic of Uzbekistan, Tashkent, fax (3712) 62 70 71. Translated from Khimiya Prirodnykh Soedinenii, No. 6, pp. 862–866, November-December, 1995. Original article submitted March 13, 1995.