Simulation of a pulsatile total artificial heart: Development of a partitioned Fluid Structure Interaction model |
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| Institution: | 1. Jožef Stefan Institute, Ljubljana, Slovenia;2. Institute of Physiology, Medical Faculty of Ljubljana, Slovenia;3. Department of Vascular Diseases, University of Ljubljana Medical Center, Slovenia;4. Institute of Biomedical Informatics, Medical Faculty of Ljubljana, Slovenia;5. Division of Hematology/Medical Oncology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA;6. Grifols, Inc., Research Triangle Park, NC, USA;7. EN-FIST Centre of Excellence, Ljubljana, Slovenia;1. Department of Civil Engineering and Architecture, University of Pavia, via Ferrata 3, Pavia, Italy;2. Department of Industrial Engineering and Informatics, University of Pavia, via Ferrata 5, Pavia, Italy;3. Inst. Advanced Study, Technical University of Munich, Lichtenbergstraße 2, Garching, Germany;4. 3D and Computer Simulation Laboratory, IRCCS Policlinico San Donato, via Morandi 30, San Donato Milanese, Italy |
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| Abstract: | Heart disease is one of the leading causes of death in the world. Due to a shortage in donor organs artificial hearts can be a bridge to transplantation or even serve as a destination therapy for patients with terminal heart insufficiency. A pusher plate driven pulsatile membrane pump, the Total Artificial Heart (TAH) ReinHeart, is currently under development at the Institute of Applied Medical Engineering of RWTH Aachen University.This paper presents the methodology of a fully coupled three-dimensional time-dependent Fluid Structure Interaction (FSI) simulation of the TAH using a commercial partitioned block-Gauss–Seidel coupling package. Partitioned coupling of the incompressible fluid with the slender flexible membrane as well as a high fluid/structure density ratio of about unity led inherently to a deterioration of the stability (‘artificial added mass instability’). The objective was to conduct a stable simulation with high accuracy of the pumping process. In order to achieve stability, a combined resistance and pressure outlet boundary condition as well as the interface artificial compressibility method was applied. An analysis of the contact algorithm and turbulence condition is presented. Independence tests are performed for the structural and the fluid mesh, the time step size and the number of pulse cycles. Because of the large deformation of the fluid domain, a variable mesh stiffness depending on certain mesh properties was specified for the fluid elements. Adaptive remeshing was avoided. Different approaches for the mesh stiffness function are compared with respect to convergence, preservation of mesh topology and mesh quality. The resulting mesh aspect ratios, mesh expansion factors and mesh orthogonalities are evaluated in detail. The membrane motion and flow distribution of the coupled simulations are compared with a top-view recording and stereo Particle Image Velocimetry (PIV) measurements, respectively, of the actual pump. |
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