SFC/FT-IR: Supercritical fluid chromatography with Fourier transform infrared detection

Fourier transform infrared spectroscopy has been utilized in the discrimination of chromatographic eluents with success. The technique of capillary supercritical fluid chromatography (SFC) offers the possibility of highly efficient and quantitative separations which avoid problems associated with gas chromatography. The technique of SCF/FT-IR utilizing a flow-through cell is described. Approaches to solutions of several of the problems inherent in flow-through cell SFC/FT-IR are described.