|
|||||
|
|
Crystallisation induced resolution of 4-fluorophenylglycine |
|
| Authors: | Jonathan D. Moseley Brian J. Williams Simon N. Owen Hugh M. Verrier |
| Affiliation: | Merck Sharp and Dohme Research Laboratories, Neuroscience Research Centre, Terlings Park, Eastwick Road, Harlow, Essex, CM20 2QR., United Kingdom |
| Abstract: | 4-Fluorophenylglycine 1 is resolved to 99.0% e.e. and 65% overall yield via its methyl ester 2 using a crystallisation induced resolution. |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ | |