| A New Cytotoxic Acetogenin from the Seeds of Annona squamosa |
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| 引用本文： | HaiHuiXIE XiaoYiWEI JiDongWANG MeiFangLIU RenZhouYANG. A New Cytotoxic Acetogenin from the Seeds of Annona squamosa[J]. 中国化学快报, 2003, 14(6): 588-590 |
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| 作者姓名： | HaiHuiXIE XiaoYiWEI JiDongWANG MeiFangLIU RenZhouYANG |
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| 作者单位： | SoutheChinaInstituteofBotany,ChineseAcademyofSciences,Guangzhou510650 |
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| 摘 要： | A New Annonaceous acetogenin,squamostolide(1),was isolated from the seeds of Annona squamosa.Its structure was elucidated based on spectroscopic methods and comparison with known compounds.It is the first example of Annonaceous acetogenin with each of the two ends of the aliphatic chain bearing a γ-lactone.Thenew compound exhibited cytotoxic activity in vitro against bel-7402 and CNE2 human tumor cell lines.
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| 关 键 词： | 细胞毒素 乙酰配基 种子 番荔枝属植物 CNE2 肿瘤细胞 抗肿瘤活性 植物药 |
A New Cytotoxic Acetogenin from the Seeds ofAnnona squamosa |
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| Hai Hui XIE,Xiao Yi WEI,Ji Dong WANG,Mei Fang LIU,Ren Zhou YANG. A New Cytotoxic Acetogenin from the Seeds ofAnnona squamosa[J]. Chinese Chemical Letters, 2003, 14(6): 588-590 |
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| Authors: | Hai Hui XIE Xiao Yi WEI Ji Dong WANG Mei Fang LIU Ren Zhou YANG |
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| Abstract: | A new Annonaceous acetogenin, squamostolide (1), was isolated from the seeds of Annona squamosa. Its structure was elucidated based on spectroscopic methods and comparison with known compounds. It is the first example of Annonaceous acetogenin with each of the two ends of the aliphatic chain bearing a g-lactone. The new compound exhibited cytotoxic activity in vitro against bel-7402 and CNE2 human tumor cell lines. |
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| Keywords: | Annona squamosa Annona acetogenins squamostolide cytotoxicity. |
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