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Tandem hydroformylation-hydrazone formation-Fischer indole synthesis: a novel approach to tryptamides
Authors:Schmidt Axel M  Eilbracht Peter
Affiliation:Universit?t Dortmund, Fachbereich Chemie, Organische Chemie I, Otto-Hahn-Str. 6, 44227 Dortmund.
Abstract:A novel one-pot synthesis of indole systems via tandem hydroformylation-hydrazone formation-Fischer indolization starting from allylic amides and aryl hydrazines is described. This tandem procedure directly leads to biologically interesting tryptamides and analogues.
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