Junceols D-H, new polyoxygenated briaranes from sea whip gorgonian coral Junceella juncea (Ellisellidae) |
| |
Authors: | Sung Ping-Jyun Pai Chen-Hao Hwang Tsong-Long Fan Tung-Yung Su Jui-Hsin Chen Jih-Jung Fang Lee-Shing Wang Wei-Hsien Sheu Jyh-Horng |
| |
Institution: | Taiwan Coral Research Center (TCRC), National Museum of Marine Biology & Aquarium (NMMBA), Checheng, Pingtung, Taiwan. pjsung@nmmba.gov.tw |
| |
Abstract: | Chemical investigations on the sea whip gorgonian coral Junceella juncea have led to the isolation of five new 8-hydroxybriarane diterpenoids, junceols D-H (1-5). The structures of briaranes 1-5 were determined on the basis of spectroscopic methods and the methylenecyclohexane rings were found to exist in boat form in these new diterpenoids. Junceols D (1) and F-H (3-5) exhibited cytotoxicity toward CCRF-CEM and DLD-1 tumor cells and junceols E-H (2-5) displayed weak inhibitory effects on superoxide anion generation by human neutrophils. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|