Catalytic enantioselective desymmetrization of meso-diamines: a dual small-molecule catalysis approach |
| |
| Authors: | De Chandra Kanta Seidel Daniel |
| |
| Institution: | Department of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, Piscataway, New Jersey 08854, USA. |
| |
| Abstract: | The desymmetrization of meso-diamines was accomplished via enantioselective monobenzoylation facilitated by the cooperative action of two small-molecule catalysts. A chiral acyl-transfer reagent is formed in situ through the interplay of benzoic anhydride, 4-(dimethylamino)pyridine as a nucleophilic catalyst, and a chiral amide-thiourea cocatalyst. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
