A highly sensitive, multiplex immunoassay using gold nanoparticle-enhanced signal amplification |
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Authors: | Han Ki-Cheol Yang Eun Gyeong Ahn Dae-Ro |
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Affiliation: | Center for Theragnosis, Biomedical Research Institute, Korea Institute of Science and Technology, Hwarangno 14-gil 5, Seongbuk-gu, Seoul 136-791, Republic of Korea. |
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Abstract: | We describe a highly sensitive, multiplex immunoassay utilizing gold nanoparticles for conjugation of detection antibodies with signal generators. The method has been compared with conventional methods and evaluated for simultaneous detection of two different biomarkers in human serum. |
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