量子点电化学发光研究进展及展望

电化学发光因具有低背景、 高灵敏度的优势已成为当前最先进的体外诊断技术之一. 以三联吡啶钌为代表的分子型电化学发光体系虽然实现了商业化应用, 但其光学性质已无法满足电化学发光分析的发展需求. 量子点作为新一代的理想发光材料在电化学发光领域表现出巨大的应用前景. 然而, 由于对量子点电化学发光的过程和机理研究尚不充分, 目前量子点电化学发光的各项性能均有待提升. 本文聚焦于量子点电化学发光领域的关键科学问题, 在总结该领域重要研究进展的基础上, 指出光谱学、 合成化学及电分析化学等多领域学科交叉是未来量子点电化学发光研究的重要发展方向.

Electrochemiluminescence of Quantum Dots: Research Progress and Future Perspectives

Electrochemiluminescence(ECL) has become one of the most advanced immunodiagnostic method due to its near-zero background and high sensitivity. Ruthenium(Ⅱ) tris(bipyridine)Ru(bpy)₃²⁺] and its derivatives have been applied in commercial diagnostics, but their optical properties can not meet the requirement of state-of-art ECL analysis. Quantum dots(QDs) possess outstanding luminescence properties and seem to be ideal for developing a new generation of ECL emitters. However, the mechanism of ECL generation from QDs deserves further in-depth investigations and the ECL performance of QDs also needs to be improved. In this review, we focus on the important advancements and key scientific issues of QDs ECL. After an overview of the developments of the field, future perspectives about the developments of QDs ECL are also exhibited. We believe that spectroscopy, synthesis chemistry and electrochemistry should be combined together to advance the research.