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Synthesis of fluoro and trifluoromethyl derivatives of 2-phenylquinolin-4-ol |
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| Authors: | Lubomir Janda Johnny Nguyen Steven E Patterson Lucjan Strekowski |
| Abstract: | A tert-butoxide base-mediated cyclization of fluoro- and trifluoromethyl-substituted Schiff bases 12-19 produces 4-tert-butoxyquinolines 23-30 which are hydrolyzed to quinolin-4-ols 31-38 . |
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