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Channel-Type Molecular Structures. Part 2. Synthesis of Bouquet-Shaped Molecules Based on a β-Cyclodextrin Core
Authors:Josette Canceill  Ludovic Jullien  Liliane Lacombe  Jean-Marie Lehn
Abstract:A new series of channel-type molecules presenting the features of potential transmembrane structures is described. They result from the grafting of amphiphilic side chains on a β-cyclodextrin derivative 3 that constitutes the organizing core. They belong to the ‘bouquet’ family (B). Compounds bearing poly(oxyethylene) side chains, Burn:x-wiley:0018019X:media:HLCA19920750315:tex2gif-stack-1 16 and 17 , and their polymethylene analogues Burn:x-wiley:0018019X:media:HLCA19920750315:tex2gif-stack-2 18 and 19 , were synthesized. The properties investigated emphasize the suitability of such molecules to be incorporated into lipid bilayer membranes.
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