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Stereospecific construction of substituted piperidines. Synthesis of (-)-paroxetine and (+)-laccarin
Authors:Bower John F  Riis-Johannessen Thomas  Szeto Peter  Whitehead Andrew J  Gallagher Timothy
Institution:School of Chemistry, University of Bristol, Bristol, UKBS8 1TS.
Abstract:Short and efficient enantioselective syntheses of (-)-paroxetine and (+)-laccarin are described based on the highly stereospecific cleavage of C(3)-substituted 1,3-cyclic sulfamidates.
Keywords:
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