Comparative investigation of elastic properties in a trabecula using micro-Brillouin scattering and scanning acoustic microscopy |
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| Authors: | Masahiko Kawabe Kenji Fukui Mami Matsukawa Mathilde Granke Amena Saïed Quentin Grimal Pascal Laugier |
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| Affiliation: | Laboratory of Ultrasonic Electronics, Doshisha University, 1-3 Tatara-Miyakodani, Kyotanabe, Kyoto 610-0321, Japan. kawabe_m@hitachizosen.co.jp |
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| Abstract: | Micro-Brillouin scattering (μ-BR) and a 200 MHz scanning acoustic microscope (SAM) with similar spatial resolutions were applied to evaluate tissue elastic properties in two directions in a trabecula. Acoustic impedance measured by SAM was in the range of 5-9 Mrayl. Wave velocities determined by μ-BR were in the range of (4.75-5.11) × 10(3) m/s. Both exhibited a similar trend of variation across the trabecula and were significantly correlated (R(2) = 0.63-0.67, p < 0.01). μ-BR is useful for the evaluation of tissue stiffness within a trabecula. Combined with SAM or nanoindentation, it can provide additional information to assess elastic anisotropy at the micro-scale. |
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