Chiral recognition in the resolution of enantiomers by GLC |
| |
| Authors: | B Koppenhoefer E Bayer |
| |
| Institution: | 1. Institut für Organische Chemie der Universit?t, Auf der Morgenstelle 18, D-7400, Tübingen, FRG
|
| |
| Abstract: | Summary Chiral recognition of many enantiomeric solutes by a chiral amide stationary phase is based mainly on hydrogen bonding. A
chiral-recognition-factor CHI is proposed, given by the difference of the enthalpy change in the enantiomer discrimination,
standardized with respect to the specific interaction of the solutes with the diamide core of the stationary phase. The r?le
of the entropy part is also discussed. By extrapolation of the retention behaviour to elevated temperature, peak inversion
of enantiomers is predicted.
Presented at the 15th International Symposium on Chromatography, Nürnberg, October 1984 |
| |
| Keywords: | Gas liquid chromatography Resolution of enantiomers Chirasil-Val Thermodynamic Parameters Chiral recognition |
| 本文献已被 SpringerLink 等数据库收录！ |
|
