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Redirecting the coat protein of a spherical virus to assemble into tubular nanostructures
Authors:Mukherjee Santanu  Pfeifer Cory M  Johnson Jennifer M  Liu Jay  Zlotnick Adam
Affiliation:Department of Biochemistry and Molecular Biology, University of Oklahoma Health Sciences Center, Oklahoma City, 73104, USA.
Abstract:We take advantage of the self-assembly properties of the coat protein of a spherical virus to form uniform tubular nanostructures. Critical to redirecting assembly are the weak interprotein association energy inherent to virus assembly and the relatively rigid nature of the double-stranded DNA scaffold at their core.
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