Redirecting the coat protein of a spherical virus to assemble into tubular nanostructures |
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Authors: | Mukherjee Santanu Pfeifer Cory M Johnson Jennifer M Liu Jay Zlotnick Adam |
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Affiliation: | Department of Biochemistry and Molecular Biology, University of Oklahoma Health Sciences Center, Oklahoma City, 73104, USA. |
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Abstract: | We take advantage of the self-assembly properties of the coat protein of a spherical virus to form uniform tubular nanostructures. Critical to redirecting assembly are the weak interprotein association energy inherent to virus assembly and the relatively rigid nature of the double-stranded DNA scaffold at their core. |
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