Silver Chloride Loaded Mesoporous Silica Particles and Their Application in the Antibacterial Coatings on Denture Base |
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Authors: | LI Xian-liang ZUO Wei-wen LUO Meng SHI Zuo-sen CUI Zhan-chen ZHU Song |
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Affiliation: | 1. State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Changchun 130012, P. R. China; 2. Hospital of Stomatology, Jilin University, Changchun 130021, P. R. China |
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Abstract: | Thiol-functionalized MCM-41 type mesoporous silica particles(MSPs) were prepared and loaded with silver chloride to act as antibacterial agents. The antibacterial activity of the silver chloride loaded MSPs(AgCl-MSPs) was evaluated by the minimum bactericidal concentration(MBC) against Candida albicans(ATCC 10231). The AgCl-MSPs with the highest antibacterial activity were then dispersed in hybrid coatings with different mass ratios to fabricate antibacterial coatings. The antibacterial activity of the coatings was tested against Candida albicans(ATCC 10231) and Streptococcus mutans(ATCC 25175). The resulting antibacterial coatings exhibited high antibacterial activity, good adhesion to the substrate and high hardness. |
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Keywords: | Mesoporous silica Silver chloride antibacterial Coating |
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