Catalytic aerobic oxidation of substituted 8-methylquinolines in Pd(II)-2,6-pyridinedicarboxylic acid systems |
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Authors: | Zhang Jing Khaskin Eugene Anderson Nicholas P Zavalij Peter Y Vedernikov Andrei N |
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Affiliation: | Department of Chemistry and Biochemistry, University of Maryland, College Park, MD 20742, USA. avederni@umd.edu. |
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Abstract: | The ability of Pd(II) complexes derived from 2,6-pyridinedicarboxylic acids to catalyze homogeneous regioselective aerobic oxidation of 5- and 6-substituted 8-methylquinolines in AcOH-Ac(2)O solution to produce corresponding 8-quinolylmethyl acetates in high yield was demonstrated; corresponding 8-quinoline carboxylic acids are minor reaction products. |
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