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Cucurbitacin glucosides from Citrullus colocynthis
Authors:Nayab Durey  Ali Dildar  Arshad Nuzhat  Malik Abdul  Choudhary M Iqbal  Ahmed Zaheer
Affiliation:International Center for Chemical Sciences, HEJ, Research Institute of Chemistry, University of Karachi, Karachi-75270, Pakistan.
Abstract:A new cucurbitacin glucoside 2-O-beta-D-glucopyranosyl-16alpha-20R-dihydroxy-cucurbita-1,5,23E,25(26)-tetraen-3,11,22-trione (1) has been isolated from the methanolic extract of the fruits of Citrulluscolocynthis. The structure has been assigned on the basis of spectral analysis including 1D and 2D NMR techniques. In addition 2-O-beta-D-glucopyranosyl-cucurbitacin B (arvenin I) (2) and 2,25-di-O-beta-D-glucopyranosyl-cucurbitacin L (3) are reported for the first time from this species.
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