Cucurbitacin glucosides from Citrullus colocynthis |
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Authors: | Nayab Durey Ali Dildar Arshad Nuzhat Malik Abdul Choudhary M Iqbal Ahmed Zaheer |
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Affiliation: | International Center for Chemical Sciences, HEJ, Research Institute of Chemistry, University of Karachi, Karachi-75270, Pakistan. |
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Abstract: | A new cucurbitacin glucoside 2-O-beta-D-glucopyranosyl-16alpha-20R-dihydroxy-cucurbita-1,5,23E,25(26)-tetraen-3,11,22-trione (1) has been isolated from the methanolic extract of the fruits of Citrulluscolocynthis. The structure has been assigned on the basis of spectral analysis including 1D and 2D NMR techniques. In addition 2-O-beta-D-glucopyranosyl-cucurbitacin B (arvenin I) (2) and 2,25-di-O-beta-D-glucopyranosyl-cucurbitacin L (3) are reported for the first time from this species. |
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